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Title details for Alzheimer's Disease and Infectious Causes by Elaine A. Moore - Available

Alzheimer's Disease and Infectious Causes

The Theory and Evidence

by Elaine A. Moore
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With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer's disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer's disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer's patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer's disease. Sources of infection in Alzheimer's disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to the gut microbiome, can reduce disease risk and improve symptoms in patients with Alzheimer's disease. This book serves as an introduction to the human microbiome and the role that infection plays in the development of Alzheimer's disease.

  • Creators

  • Series

    McFarland Health Topics

  • Publisher

  • Release date

    April 1, 2020

  • Formats

    • Kindle Book

    • OverDrive Read

      • ISBN: 9781476638911

    • EPUB ebook

      • ISBN: 9781476638911
      • File size: 6830 KB

  • Languages

    • English

  • Reviews

    • Library Journal

      May 1, 2020

      Moore (Encyclopedia of Alzheimer's Disease) is a medical technologist, as well as a series editor for McFarland Health Topics. Her writing is informed by her knowledge of medical literature, but her accessible prose allows any interested patient or caregiver to understand recent advances in various topics. This volume in the "Health Topics" series focuses on the various viruses, prions, bacteria, fungal, and protozoan infections that research has linked to the development of Alzheimer's disease. Moore starts with basic information about Alzheimer's disease, and includes accessible data on genetic and environmental risk factors implicated in research, but the focus is on infectious causes. Recent microbiome research is included. Risk reduction strategies based on diet, exercise, other lifestyle changes, and experimental treatments are discussed. References are extensive throughout the book, and there are some illustrations to explain basic concepts. VERDICT An excellent book for patients, caregivers, and those who are learning about infectious causes of Alzheimer's disease.--Margaret Henderson, Ramona, CA

      Copyright 2020 Library Journal, LLC Used with permission.

Formats

  • Kindle Book
  • OverDrive Read
  • EPUB ebook

subjects

Languages

  • English

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